UTAR researcher’s quest at Tsinghua University

“This century-old institution welcomed me with budding phoenix trees, cherry blossoms poised to bloom, and red-brick buildings standing in quiet contemplation, a unique atmosphere where rationality and poetic charm intertwine,” expressed Dr Amy Saik Yi Hsan, Chairperson of the Centre for Stem Cell Research.

In March 2025, Dr Amy Saik embarked on a four-month visiting scholar programme at Tsinghua University, carrying with her the blessings and support of UTAR President Ir Prof Dato’ Dr Ewe Hong Tat and M. Kandiah Faculty of Medicine and Health Sciences Dean Prof Dr Thong Meow Keong.

During her stay at Tsinghua University, Dr Amy Saik was hosted by Prof Kee Kehkooi from the School of Basic Medical Sciences, a distinguished scientist who was personally invited by Malaysia’s Prime Minister, Dato’ Seri Anwar Ibrahim, to return and contribute to his homeland. Prof Kee and his research team are renowned for developing an in vitro differentiation system for human germ cells, a pioneering achievement that contributed to China’s national space programme, specifically the Tianzhou-1 mission.

Building on this collaboration, Dr Amy Saik’s research with Prof Kee focused on investigating the differentiation mechanisms of reproductive stem cells — a profound and complex field that delves into the very origins of life. She shared, “What made this endeavour particularly exciting was our attempt to seek solutions from traditional Chinese medicine (TCM). By screening bioactive compounds such as astragaloside and icariin, we explored their potential to promote the differentiation of reproductive stem cells. In the laboratory, we witnessed the fascinating convergence of traditional herbal medicine and modern biotechnology. Certain TCM-derived bioactive compounds indeed demonstrated unique effects in promoting germ cell differentiation and maturation, offering new hope for the treatment of male infertility. This reinforced our belief that the innovative integration of Chinese and Western medicine holds immense potential.”

Reflecting on her broader academic experience, Dr Amy Saik remarked, “The academic environment at Tsinghua University was truly dynamic. I was especially inspired by a sharing session led by a professor from MIT, who elaborated on how research output could be commercialised, revealing another dimension of scientific research. At the 2025 Zhongguancun Forum, innovations ranging from AI-assisted diagnostics to high-performance biomaterials captivated my attention. These experiences profoundly reshaped my understanding of the value of scientific research — excellent work should not only be published in academic journals but also reach and serve the community.”

She further observed, “Tsinghua’s academic environment showcases a distinctive ‘China speed’. Faculty members and students here truly embody the university’s motto ‘Actions speak louder than words’ through rigorous research planning and efficient experimental execution. Although I went through an initial adaptation period, I soon realised that this very efficiency was the key driver of breakthroughs. It taught me how to maintain research quality while optimising time management and enhancing productivity.”

Looking beyond the laboratory, Dr Amy Saik shared, “Beyond research, my favourite moments were the evening strolls along the Lotus Pond. The elegance once described by Zhu Ziqing unfolded before my eyes — gentle ripples on the water and willow branches swaying along the shore added a poetic touch to the otherwise rigorous scientific life. I also cherished the opportunities to share and exchange ideas with scholars from around the world in Tsinghua’s historic library; truly a delightful experience.”

She concluded with heartfelt reflection, “This time at Tsinghua not only deepened my understanding of reproductive stem cell research but also allowed me to experience firsthand the seamless integration of tradition and modernity, and the harmony between Eastern and Western academic cultures. With these invaluable insights, I look forward to bringing Tsinghua’s spirit and innovation back to Malaysia, back to UTAR, and to continuing my exploration in the field of reproductive medicine, contributing my part to the advancement of science. This journey will undoubtedly nourish my academic path for years to come.”